Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL2922617 | 0.98 | GPR84 (0.56) | GPR84FFAR1FFAR4LMNAMEN1 | |
| Adipic Acid SCHEMBL11579367 | 0.98 | GPR84 (0.56) | GPR84FFAR1FFAR4LMNAMEN1 | |
| Tetraethylene Glycol SCHEMBL11643281 | 0.98 | GPR84 (0.56) | GPR84FFAR1FFAR4LMNAMEN1 | |
| Adipic Acid SCHEMBL28497473 | 0.98 | GPR84 (0.56) | GPR84FFAR1FFAR4LMNAMEN1 | |
| Tetraethylene Glycol SCHEMBL17144180 | 0.95 | GPR84 (0.61) | GPR84FFAR1FFAR4LMNAMEN1 | |
| Sebacic Acid SCHEMBL11108127 | 0.95 | GPR84 (0.61) | GPR84FFAR1FFAR4LMNAMEN1 | |
| Sebacic Acid SCHEMBL1121757 | 0.95 | GPR84 (0.61) | GPR84FFAR1FFAR4LMNAMEN1 | |
| Sebacic Acid SCHEMBL1532508 | 0.95 | GPR84 (0.61) | GPR84FFAR1FFAR4LMNAMEN1 | |
| Triethylene Glycol SCHEMBL28474002 | 0.95 | GPR84 (0.61) | GPR84FFAR1FFAR4LMNAMEN1 | |
| Adipic Acid SCHEMBL207584 | 0.95 | GPR84 (0.59) | GPR84FFAR1FFAR4LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784448-B1 | WATER SOLUBLE POLYAMIDE COMPOSITIONS, SOLUTIONS THEREOF, FILMS AND SHEETS THEREFROM AND PROCESS OF MAKING FILMS AND SHEETS THEREFROM | DU PONT (US) | 2008-12-31 | — | — | EP | disclosed |
| EP-1784448-A1 | WATER SOLUBLE POLYAMIDE COMPOSITIONS, SOLUTIONS THEREOF, FILMS AND SHEETS THEREFROM AND PROCESS OF MAKING FILMS AND SHEETS THEREFROM | E.I.Du pont de nemours and company (US) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006029138-A1 | WATER SOLUBLE POLYAMIDE COMPOSITIONS, SOLUTIONS THEREOF, FILMS AND SHEETS THEREFROM AND PROCESS OF MAKING FILMS AND SHEETS THEREFROM | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |
| US-20060052505-A1 | Water soluble polyamide compositions, solutions thereof, films and sheets therefrom and process of making films and sheets therefrom | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-03-09 | — | — | US | disclosed |