SCHEMBL4663347

SCHEMBL4663347

CC(C)c1ccc(C(C)(C)OOC(=O)c2ccccc2C(=O)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
TDP1 Q9NUW8 2/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ELANE P08246 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
CYP2C9 P11712 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
AKR1C3 P42330 2/20 0.40
CYP2D6 P10635 1/20 0.39
HIF1A Q16665 1/20 0.39
PPARG P37231 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HPGD P15428 1/20 0.38
XBP1 P17861 1/20 0.38
BCL2 P10415 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6847666 0.88 ALDH1A1 (0.50) ALDH1A1TDP1TSHRHSD17B10ELANE
SCHEMBL4595204 0.87 ALDH1A1 (0.38) ALDH1A1TDP1TSHRHSD17B10ELANE
SCHEMBL4595202 0.81 CYP2D6 (0.37) ALDH1A1TDP1TSHRHSD17B10ELANE
SCHEMBL80421 0.81 CYP2C9 (0.37) ALDH1A1TDP1L3MBTL1CYP2C9CYP2D6
SCHEMBL7907953 0.79 ALDH1A1 (0.49) ALDH1A1TDP1TSHRHSD17B10ELANE
SCHEMBL1815675 0.78 ALDH1A1 (0.69) ALDH1A1TDP1TSHRHSD17B10ELANE
SCHEMBL29388336 0.78 ALDH1A1 (0.69) ALDH1A1TDP1TSHRHSD17B10ELANE
SCHEMBL9745149 0.76 TDP1 (0.70) ALDH1A1TDP1TSHRHSD17B10L3MBTL1
SCHEMBL268229 0.74 ALDH1A1 (0.44) ALDH1A1TDP1TSHRHSD17B10ELANE
SCHEMBL9795518 0.74 ALDH1A1 (0.50) ALDH1A1TDP1TSHRHSD17B10ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0520364-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1997-09-17 EP claimed
CN-108698427-B Cylindrical printing plate, cylindrical printing plate precursor, and method for producing same 富士胶片株式会社 2020-01-14 CN disclosed
US-20150197079-A1 PROCESS FOR PRODUCING CYLINDRICAL PRINTING PLATE PRECURSOR, CYLINDRICAL PRINTING PLATE AND PROCESS FOR MAKING SAME FUJIFILM CORPORATION (JP) 2015-07-16 US disclosed
EP-1449651-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2008-10-29 EP disclosed
US-20080184930-A1 INK-JET RECORDING DEVICE FUJIFILM CORPORATION (JP) 2008-08-07 US disclosed
US-20060005725-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2006-01-12 US disclosed
US-6858373-B2 Photosensitive composition and negative working lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2005-02-22 US disclosed
US-20030091933-A1 Photosensitive composition and negative working lithographic printing plate FUJIFILM CORPORATION (JP) 2003-05-15 US disclosed