⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948546 | 0.82 | — | — | |
| SCHEMBL895220 | 0.75 | — | — | |
| SCHEMBL8758 | 0.75 | — | — | |
| SCHEMBL11792566 | 0.71 | — | — | |
| SCHEMBL2409777 | 0.71 | — | — | |
| SCHEMBL767081 | 0.71 | — | — | |
| SCHEMBL1269421 | 0.69 | PTPN1 (0.48) | — | |
| SCHEMBL1269417 | 0.69 | PTPN1 (0.48) | — | |
| SCHEMBL797340 | 0.68 | — | — | |
| Ethylene SCHEMBL6511490 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091945-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2014-01-15 | — | — | EP | claimed |
| CN-103374130-A | Aromatic polyimide film, preparation method and application thereof | TAIMIDE TECHNOLOGY INC | 2013-10-30 | — | — | CN | claimed |
| US-5917034-A | Antithrombotic n-amidinopiperidine and benzamidine derivatives | PFIZER INC. (US) | 1999-06-29 | — | — | US | claimed |
| EP-0858458-A1 | ANTITHROMBOTIC N-AMIDINOPIPERIDINE AND BENZAMIDINE DERIVATIVES | Pfizer Limited (GB) | 1998-08-19 | — | — | EP | claimed |
| WO-1997016444-A1 | ANTITHROMBOTIC N-AMIDINOPIPERIDINE AND BENZAMIDINE DERIVATIVES | PFIZER LIMITED (GB) | 1997-05-09 | — | — | WO | claimed |
| EP-3512852-B1 | TRAF 6 INHIBITORS | HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) | 2024-06-26 | — | — | EP | disclosed |
| US-11931412-B2 | JAK1 inhibitors and uses thereof | WASHINGTON UNIVERSITY (US) | 2024-03-19 | — | — | US | disclosed |
| CN-109715631-B | TRAF6 inhibitors | 德国亥姆霍兹慕尼黑中心健康与环境研究中心（有限公司） | 2022-02-18 | — | — | CN | disclosed |
| US-11185548-B2 | Inhibitors of cytochrome P450 family 7 subfamily B member 1 (CYP7B1) for use in treating diseases | HELMHOLTZ ZENTRUM MUNCHEN—DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2021-11-30 | — | — | US | disclosed |
| US-20210338812-A1 | JAK1 INHIBITORS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2021-11-04 | — | — | US | disclosed |
| US-11001591-B2 | TRAF 6 inhibitors | HELMHOLTZ ZENTRUM MUENCHEN—DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2021-05-11 | — | — | US | disclosed |
| US-10973913-B2 | JAK inhibitors and uses thereof | WASHINGTON UNIVERSITY (US) | 2021-04-13 | — | — | US | disclosed |
| US-4622417-A | DIETETICS | GENERAL FOODS CORPORATION (US) | 1986-11-11 | — | — | US | disclosed |
| EP-0199258-A2 | L-Aminodicarboxylic acid amides and an edible composition containing same | GENERAL FOODS CORPORATION (US) | 1986-10-29 | — | — | EP | disclosed |
| US-4619782-A | L-aminodicarboxylic acid gem-diamines | GENERAL FOODS CORPORATION (US) | 1986-10-28 | — | — | US | disclosed |
| EP-0186173-A2 | L-Aminodicarboxylic-(0-cycloalkyl)-L-aminocarboxylate alkyl esters, an edible composition containing same as sweeteners and a method for sweetening an edible composition | GENERAL FOODS CORPORATION (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4572799-A | L-Aminodicarboxylic acid amides | GENERAL FOODS CORPORATION (US) | 1986-02-25 | — | — | US | disclosed |
| EP-0029657-A2 | Pesticidal tetrazines, their use and compositions, processes for their preparation and preparation intermediates | FBC LIMITED (GB) | 1981-06-03 | — | — | EP | disclosed |
| US-4026910-A | Oxidation process using nickel peroxide oxidizing agents | HOFFMANN-LA ROCHE INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-3994936-A | Catalytic rearrangement | HOFFMANN-LA ROCHE INC. (US) | 1976-11-30 | — | — | US | disclosed |