Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ABL1 | P00519 | 5/20 | 0.41 |
| ▸ | BCR | P11274 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4663889 | 0.81 | ABCB1 (0.52) | ABCB1ABCG2EGFRABL1BCR | |
| SCHEMBL4663903 | 0.78 | ABCB1 (0.52) | ABCB1ABCG2EGFRABL1BCR | |
| SCHEMBL4666216 | 0.71 | ABCB1 (0.50) | ABCB1ABCG2EGFRCYP1A2CYP2D6 | |
| SCHEMBL19089319 | 0.66 | EGFR (0.52) | ABCB1ABCG2EGFRCYP1A2CYP2D6 | |
| Formic Acid SCHEMBL4666175 | 0.65 | PRKCA (0.39) | ABCB1ABCG2EGFRCYP1A2CYP2D6 | |
| SCHEMBL4666155 | 0.65 | CYP1A2 (0.48) | ABL1BCRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL27979836 | 0.64 | CA12 (0.47) | — | |
| SCHEMBL4664366 | 0.63 | ABL1 (0.45) | ABL1BCRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4667395 | 0.63 | CYP1A2 (0.46) | ABL1BCRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL26637953 | 0.63 | EGFR (0.53) | ABCG2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | ABCB1 1292/4885ABCG2 667/4885EGFR 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.