⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40239 | 0.75 | MEN1 (0.39) | — | |
| SCHEMBL14104841 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL6299865 | 0.70 | — | — | |
| SCHEMBL12020545 | 0.68 | — | — | |
| SCHEMBL4865642 | 0.67 | MEN1 (0.34) | — | |
| SCHEMBL13865255 | 0.66 | — | — | |
| SCHEMBL39209 | 0.66 | — | — | |
| SCHEMBL12020479 | 0.66 | ALDH1A1 (0.36) | — | |
| SCHEMBL8463169 | 0.65 | ALDH1A1 (0.33) | — | |
| Nitrilotriacetic Acid SCHEMBL3801359 | 0.65 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1949144-A2 | RADIATION-ABSORBING POLYMERIC MATERIALS AND OPHTHALMIC DEVICES COMPRISING SAME | BAUSCH & LOMB INCORPORATED (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007050395-A2 | RADIATION-ABSORBING POLYMERIC MATERIALS AND OPHTHALMIC DEVICES COMPRISING SAME | BAUSCH & LOMB INCORPORATED (US) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007050394-A2 | POLYMERIC RADIATION-ABSORBING MATERIALS AND OPHTHALMIC DEVICES COMPRISING SAME | BAUSCH & LOMB INCORPORATED (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20070092831-A1 | Radiation-absorbing polymeric materials and ophthalmic devices comprising same | BAUSCH & LOMB INCORPORATED | 2007-04-26 | — | — | US | disclosed |
| US-20070092830-A1 | Polymeric radiation-absorbing materials and ophthalmic devices comprising same | BAUSCH & LOMB INCORPORATED | 2007-04-26 | — | — | US | disclosed |
| WO-2006119304-A1 | RADIATION-ABSORBING POLYMERIC MATERIALS AND OPHTHALMIC DEVICES COMPRISING SAME | BAUSCH & LOMB INCORPORATED (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20060252850-A1 | Radiation-absorbing polymeric materials and ophthalmic devices comprising same | BAUSCH & LOMB INCORPORATED | 2006-11-09 | — | — | US | disclosed |