Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799647 | 0.84 | NR1H4 (0.54) | BCHEBAZ2BHTTALDH1A1LMNA | |
| SCHEMBL3304144 | 0.82 | BCHE (0.47) | BCHEBAZ2BHTTALDH1A1LMNA | |
| SCHEMBL13799645 | 0.80 | TSHR (0.45) | BCHEBAZ2BHTTALDH1A1LMNA | |
| SCHEMBL24159031 | 0.76 | P2RX7 (0.47) | HTTALDH1A1LMNACYP3A4SMN1; SMN2 | |
| SCHEMBL9965045 | 0.74 | BCHE (0.49) | BCHEBAZ2BHTTALDH1A1LMNA | |
| SCHEMBL13205786 | 0.73 | BCHE (0.49) | BCHEBAZ2BHTTALDH1A1LMNA | |
| SCHEMBL21894060 | 0.72 | BCHE (0.47) | BCHEBAZ2BHTTALDH1A1LMNA | |
| SCHEMBL292212 | 0.72 | BCHE (0.47) | BCHEBAZ2BHTTALDH1A1LMNA | |
| SCHEMBL964527 | 0.72 | BCHE (0.51) | BCHEBAZ2BHTTALDH1A1LMNA | |
| SCHEMBL7374141 | 0.71 | KDM4E (0.47) | ALDH1A1LMNASMN1; SMN2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007717-A1 | NOVEL SULFONAMIDE COMPOUNDS | Actelion Pharmaceuticals Ltd. (CH) | 2008-12-31 | — | — | EP | claimed |
| WO-2007116374-A1 | NOVEL SULFONAMIDE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2007-10-18 | — | — | WO | claimed |