Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.76 |
| ▸ | SCP2 | P22307 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.42 |
| ▸ | GLA | P06280 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56792 | 0.96 | MEN1 (0.76) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL16696324 | 0.88 | MEN1 (0.61) | MEN1KMT2ANPC1POLBRAB9A | |
| Nile Red SCHEMBL49047 | 0.86 | MEN1 (1.00) | MEN1KMT2ANPC1POLBRAB9A | |
| Nile Red SCHEMBL29373685 | 0.86 | MEN1 (1.00) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL23733292 | 0.86 | MEN1 (0.58) | MEN1KMT2ANPC1POLBRAB9A | |
| Nile Red SCHEMBL28703996 | 0.86 | MEN1 (0.93) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL15398206 | 0.84 | MEN1 (0.78) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL15398222 | 0.84 | MEN1 (0.78) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL7815643 | 0.84 | MEN1 (0.60) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL23244667 | 0.83 | MEN1 (0.70) | MEN1KMT2ANPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210115000-A1 | NILE RED DERIVATIVES FOR IMPROVED RATIOMETRIC IMAGING FOR NERVE SPECIFIC CONTRAST | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2021-04-22 | — | — | US | disclosed |
| US-20210115000-A1 | NILE RED DERIVATIVES FOR IMPROVED RATIOMETRIC IMAGING FOR NERVE SPECIFIC CONTRAST | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2021-04-22 | — | — | US | disclosed |
| EP-2695930-B1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE, NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE | DAINIPPON INK & CHEMICALS (JP) | 2019-09-11 | — | — | EP | disclosed |
| US-9475991-B2 | Polymerizable liquid crystal composition, polarized light-emitting coating material, novel naphtholactam derivative novel coumarin derivative, novel nile red derivative, and novel anthracene derivative | ADEKA CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |
| US-9475991-B2 | Polymerizable liquid crystal composition, polarized light-emitting coating material, novel naphtholactam derivative novel coumarin derivative, novel nile red derivative, and novel anthracene derivative | ADEKA CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |
| EP-2695930-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE, NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE | Adeka Corporation (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-20130334461-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE | ADEKA CORPORATION (JP) | 2013-12-19 | — | — | US | disclosed |
| US-20130334461-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE | ADEKA CORPORATION (JP) | 2013-12-19 | — | — | US | disclosed |
| US-20080038840-A1 | Fluorescent Method And Compounds To Monitor Protein-Lipid Binding | EUROPAEISCHES LABORATORIUM FUER MOLEKULARBIOLOGIE (DE) | 2008-02-14 | — | — | US | disclosed |
| EP-1747207-A1 | FLUORESCENT METHOD AND COMPOUNDS TO MONITOR PROTEIN-LIPID BINDING | EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE (EMBL) (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005113524-A1 | FLUORESCENT METHOD AND COMPOUNDS TO MONITOR PROTEIN-LIPID BINDING | Europäisches Laboratorium für Molekularbiologie (EMBL) (DE) | 2005-12-01 | — | — | WO | disclosed |
| EP-1595872-A1 | Fluorescent compounds for monitoring protein-lipid binding | EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE (EMBL) (DE) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038840-A1 | Fluorescent Method And Compounds To Monitor Protein-Lipid Binding | DBI, CETP, SREBF1 | MEN1 3143/4885KMT2A 2814/4885NPC1 14/4885 |
| US-20210115000-A1 | NILE RED DERIVATIVES FOR IMPROVED RATIOMETRIC IMAGING FOR NERVE SPECIFIC CONTRAST | FABP4, LRBA, FABP7 | MEN1 3010/4885KMT2A 4468/4885NPC1 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.