Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.38 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29393434 | 0.94 | DHODH (0.39) | DHODHCARM1PDE4BKLKB1STIM1 | |
| SCHEMBL1380391 | 0.94 | DHODH (0.39) | DHODHCARM1PDE4BKLKB1STIM1 | |
| SCHEMBL27601648 | 0.91 | PDE4B (0.37) | DHODHCARM1PDE4BKLKB1STIM1 | |
| SCHEMBL782369 | 0.91 | PDE4B (0.37) | DHODHCARM1PDE4BKLKB1STIM1 | |
| SCHEMBL12911831 | 0.90 | CARM1 (0.43) | DHODHCARM1PDE4BKLKB1STIM1 | |
| SCHEMBL13104897 | 0.89 | PDE4B (0.38) | DHODHPDE4BMEN1KMT2A | |
| SCHEMBL13104904 | 0.89 | MALT1 (0.38) | CARM1PDE4B | |
| SCHEMBL13104851 | 0.88 | KLKB1 (0.38) | CARM1PDE4BKLKB1 | |
| SCHEMBL951001 | 0.88 | KLKB1 (0.43) | CARM1KLKB1STIM1ORAI1MEN1 | |
| SCHEMBL14360665 | 0.88 | KDM4E (0.37) | DHODHCARM1PDE4BKLKB1STIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265850-B1 | INSECTICIDAL ANTHRANILAMIDES | DU PONT (US) | 2007-01-03 | — | — | EP | claimed |
| US-20040142984-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2004-07-22 | — | — | US | claimed |
| US-6747047-B2 | ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-06-08 | — | — | US | claimed |
| US-20030229050-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2003-12-11 | — | — | US | claimed |
| EP-1700845-B1 | Insecticidal anthranilamides | DU PONT (US) | 2008-12-10 | — | — | EP | disclosed |
| US-7338978-B2 | Insecticidal anthranilamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1265850-B1 | INSECTICIDAL ANTHRANILAMIDES | DU PONT (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1700845-A1 | Insecticidal anthranilamides | E.I.Du pont de nemours and company (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20060079561-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2006-04-13 | — | — | US | disclosed |
| US-6995178-B2 | Insecticidal anthranilamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-20040142984-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2004-07-22 | — | — | US | disclosed |
| US-6747047-B2 | ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-06-08 | — | — | US | disclosed |
| US-20030229050-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2003-12-11 | — | — | US | disclosed |
| EP-1265850-A2 | INSECTICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070671-A2 | INSECTICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142984-A1 | Insecticidal anthranilamides | ANTXR2, NIT2, AKR7A2 | DHODH 1701/4885CARM1 1742/4885PDE4B 929/4885 |
| US-20060079561-A1 | Insecticidal anthranilamides | ANTXR2, CYB5R3, NIT2 | DHODH 1384/4885CARM1 1777/4885PDE4B 866/4885 |
| US-20030229050-A1 | Insecticidal anthranilamides | ANTXR2, NIT2, CYB5R3 | DHODH 1937/4885CARM1 1812/4885PDE4B 825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.