Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775666 | 0.75 | CYP2D6 (0.47) | CYP2D6OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL9524001 | 0.75 | CYP2D6 (0.47) | CYP2D6OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL2337932 | 0.75 | CYP2D6 (0.65) | CYP2D6OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL868771 | 0.74 | CYP2D6 (0.50) | CYP2D6OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL868770 | 0.74 | CYP2D6 (0.50) | CYP2D6OPRL1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL2330314 | 0.73 | CYP2D6 (0.63) | CYP2D6OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL18925628 | 0.73 | CYP2D6 (0.31) | CYP2D6 | |
| SCHEMBL1586464 | 0.73 | CYP2D6 (0.68) | CYP2D6OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL10819303 | 0.71 | CYP2D6 (0.60) | CYP2D6OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL28219815 | 0.71 | CYP2D6 (0.60) | CYP2D6OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930321-A1 | PROCESS FOR PREPARATION OF TETRASUBSTITUTED 5-AZASPIRO[2.4]- HEPTANE DERIVATIVES AND OPTICALLY ACTIVE INTERMEDIATES THEREOF | Daiichi Sankyo Company, Limited (JP) | 2008-06-11 | — | — | EP | claimed |