Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762295 | 0.84 | GAA (0.58) | SIGMAR1OPRM1ACHE | |
| SCHEMBL83250 | 0.84 | GAA (0.58) | SIGMAR1OPRM1ACHE | |
| SCHEMBL762150 | 0.84 | GAA (0.58) | SIGMAR1OPRM1ACHE | |
| SCHEMBL14089987 | 0.71 | SLC6A3 (0.53) | SLC6A3SIGMAR1ACHE | |
| SCHEMBL14159659 | 0.70 | GAA (0.57) | SIGMAR1OPRM1ACHE | |
| SCHEMBL15470506 | 0.70 | SLC6A3 (0.51) | SLC6A3SIGMAR1OPRM1 | |
| SCHEMBL27727731 | 0.70 | SLC6A3 (0.61) | SLC6A3SIGMAR1 | |
| SCHEMBL8970787 | 0.70 | SLC6A3 (0.56) | SLC6A3SIGMAR1OPRM1ACHESMN1; SMN2 | |
| SCHEMBL5363319 | 0.70 | SMN1; SMN2 (0.56) | SLC6A3SIGMAR1OPRM1SMN1; SMN2KCNH2 | |
| SCHEMBL27674276 | 0.70 | SLC6A3 (0.47) | SLC6A3SIGMAR1OPRM1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930321-A1 | PROCESS FOR PREPARATION OF TETRASUBSTITUTED 5-AZASPIRO[2.4]- HEPTANE DERIVATIVES AND OPTICALLY ACTIVE INTERMEDIATES THEREOF | Daiichi Sankyo Company, Limited (JP) | 2008-06-11 | — | — | EP | claimed |