Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.75 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.75 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28304097 | 0.93 | PTGS1 (0.88) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL10825773 | 0.93 | PTGS1 (0.88) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL1479109 | 0.93 | PTGS1 (0.88) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| Glutathione SCHEMBL711491 | 0.93 | PTGS1 (0.88) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL14360534 | 0.93 | PTGS1 (0.88) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL6905290 | 0.91 | PTGS1 (0.68) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL10324537 | 0.90 | PTGS1 (0.92) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL2355650 | 0.90 | PTGS1 (0.92) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| Glutathione SCHEMBL29707170 | 0.89 | PTGS1 (0.95) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| Glutathione SCHEMBL27952966 | 0.89 | PTGS1 (0.95) | PTGS1GSTK1GLO1FOLH1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080279794-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | BASCHONG WERNER | 2008-11-13 | — | — | US | disclosed |
| US-20080260667-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | BASCHONG WERNER | 2008-10-23 | — | — | US | disclosed |
| US-20070219275-A1 | Use of Benzophenone Uv Filters for Preventing Tanning | BASCHONG WERNER | 2007-09-20 | — | — | US | disclosed |
| EP-1737419-A2 | USE OF BENZOPHENONE UV FILTERS FOR PREVENTING TANNING | Ciba SC Holding AG (CH) | 2007-01-03 | — | — | EP | disclosed |
| US-20060216252-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-09-28 | — | — | US | disclosed |
| EP-1648400-A1 | USE OF HALOGENATED HYDROXYDIPHENYL ETHER COMPOUNDS FOR THE TREATMENT OF THE SKIN | Ciba SC Holding AG (CH) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005094772-A2 | USE OF BENZOPHENONE UV FILTERS FOR PREVENTING TANNING | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-13 | — | — | WO | disclosed |
| WO-2005013931-A1 | USE OF HALOGENATED HYDROXYDIPHENYL ETHER COMPOUNDS FOR THE TREATMENT OF THE SKIN | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-02-17 | — | — | WO | disclosed |
| EP-1366757-A1 | Use of hydroxydiphenylether compounds for the treatment of skin | Ciba SC Holding AG (CH) | 2003-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219275-A1 | Use of Benzophenone Uv Filters for Preventing Tanning | C1R, CBR3, AOC3 | PTGS1 4072/4885GSTK1 1446/4885GLO1 1296/4885 |
| US-20080260667-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | MC1R, TYR, MC3R | PTGS1 1830/4885GSTK1 1314/4885GLO1 1954/4885 |
| US-20080279794-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | MC1R, TYR, MC3R | PTGS1 1830/4885GSTK1 1314/4885GLO1 1954/4885 |
| US-20060216252-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | MC1R, TYR, MC3R | PTGS1 1739/4885GSTK1 1624/4885GLO1 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.