Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.68 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | GNPAT | O15228 | 2/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665326 | 0.91 | PTGS1 (0.75) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL1479109 | 0.88 | PTGS1 (0.88) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL28304097 | 0.88 | PTGS1 (0.88) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL10825773 | 0.88 | PTGS1 (0.88) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL14360534 | 0.88 | PTGS1 (0.88) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL29420383 | 0.86 | PTGS1 (0.68) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL10324537 | 0.86 | PTGS1 (0.92) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL2355650 | 0.86 | PTGS1 (0.92) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL30439788 | 0.85 | FOLH1 (0.58) | PTGS1GSTK1FOLH1GNPATBMP1 | |
| SCHEMBL14538441 | 0.85 | PTGS1 (0.55) | PTGS1GSTK1GLO1NOD1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131340-B1 | HEXAPEPTIDE WITH THE STABILIZED DISULFIDE BOND AND DERIVATIVES THEREOF REGULATING METABOLISM, PROLIFERATION, DIFFERENTIATION AND APOPTOSIS | NOVELOS THERAPEUTICS INC (US) | 2004-10-13 | — | — | EP | claimed |