Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.48 |
| ▸ | BCR | P11274 | 9/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL4666082 | 0.96 | HRH3 (0.53) | ABL1BCRHRH3MAPTKIT | |
| Formic Acid SCHEMBL4664287 | 0.94 | ABL1 (0.47) | ABL1BCRHRH3MAPTKIT | |
| Formic Acid SCHEMBL4663881 | 0.94 | HRH3 (0.48) | ABL1BCRHRH3CYP3A4FGFR3 | |
| SCHEMBL4666140 | 0.90 | ABL1 (0.49) | ABL1BCRMAPTKIT | |
| Formic Acid SCHEMBL4665720 | 0.90 | HRH3 (0.53) | ABL1BCRHRH3MAPTKIT | |
| SCHEMBL4665728 | 0.89 | LMNA (0.51) | ABL1BCRJAK2JAK3PTK2 | |
| Formic Acid SCHEMBL4665817 | 0.88 | ABL1 (0.43) | ABL1BCRHRH3MAPT | |
| Formic Acid SCHEMBL4665830 | 0.88 | ABL1 (0.47) | ABL1BCRHRH3MAPTKIT | |
| Formic Acid SCHEMBL4663832 | 0.87 | AXL (0.47) | ABL1BCRHRH3CYP3A4FGFR3 | |
| Formic Acid SCHEMBL4666189 | 0.86 | ABL1 (0.46) | ABL1BCRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | ABL1 24/4885BCR 402/4885HRH3 887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.