Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.39 |
| ▸ | BCR | P11274 | 14/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664370 | 0.96 | ABL1 (0.38) | ABL1BCRHTR6TP53TNNI3K | |
| SCHEMBL4667474 | 0.94 | BACE1 (0.35) | ABL1BCRHTR6TP53EGFR | |
| SCHEMBL4666209 | 0.91 | ABL1 (0.38) | ABL1BCRTP53TNNI3KEGFR | |
| SCHEMBL4666098 | 0.90 | BPTF (0.35) | ABL1BCRHTR6TP53 | |
| SCHEMBL4664340 | 0.89 | BACE1 (0.35) | ABL1BCRTP53TNNI3KEGFR | |
| SCHEMBL4666028 | 0.89 | ABL1 (0.38) | ABL1BCRTNNI3KCCNT1CDK9 | |
| SCHEMBL4665744 | 0.89 | MEN1 (0.38) | ABL1BCRHTR6TP53EGFR | |
| SCHEMBL4664313 | 0.88 | HTR6 (0.42) | ABL1BCRHTR6TNNI3KCCNT1 | |
| SCHEMBL4665757 | 0.88 | HTR6 (0.35) | ABL1BCRHTR6TP53EGFR | |
| SCHEMBL4665626 | 0.87 | BPTF (0.39) | ABL1BCRHTR6CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | ABL1 24/4885BCR 402/4885HTR6 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.