Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.64 |
| ▸ | CTSS | P25774 | 1/20 | 0.64 |
| ▸ | CTSK | P43235 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.60 |
| ▸ | TACR1 | P25103 | 2/20 | 0.59 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | CCKBR | P32239 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5467203 | 1.00 | CTSL (0.64) | CTSLCTSSCTSKHDAC3HDAC4 | |
| SCHEMBL4666077 | 1.00 | CTSL (0.64) | CTSLCTSSCTSKHDAC3HDAC4 | |
| SCHEMBL14265326 | 0.90 | CTSL (0.62) | CTSLCTSSCTSKHDAC3HDAC4 | |
| SCHEMBL23127370 | 0.89 | ACE (0.66) | CTSLCTSSCTSKHDAC3HDAC4 | |
| SCHEMBL28555823 | 0.89 | ACE (0.66) | CTSLCTSSCTSKHDAC3HDAC4 | |
| SCHEMBL29401065 | 0.89 | CTSL (0.63) | CTSLCTSSCTSKHDAC3HDAC4 | |
| SCHEMBL6409052 | 0.89 | CTSL (0.63) | CTSLCTSSCTSKHDAC3HDAC4 | |
| SCHEMBL29398124 | 0.89 | CTSL (0.63) | CTSLCTSSCTSKHDAC3HDAC4 | |
| SCHEMBL3560147 | 0.89 | CTSL (0.63) | CTSLCTSSCTSKHDAC3HDAC4 | |
| SCHEMBL6833548 | 0.89 | CTSL (0.63) | CTSLCTSSCTSKHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287493-A1 | ARYLMETHYLEN SUBSTITUTED N-ACYL-Y-AMINOALCOHOLS | BAYER SCHERING PHARMA AG (DE) | 2008-11-20 | — | — | US | disclosed |
| EP-1985612-A1 | Arymethylen substituted N-Acyl-gamma-aminoalcohols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287493-A1 | ARYLMETHYLEN SUBSTITUTED N-ACYL-Y-AMINOALCOHOLS | FSHR, CYP19A1, GNRHR | CTSL 3200/4885CTSS 3539/4885CTSK 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.