Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709135 | 0.95 | NR1H4 (0.52) | NR1H4KMT2AATMELANE | |
| SCHEMBL14677825 | 0.92 | NR1H4 (0.62) | NR1H4KMT2AATMELANE | |
| SCHEMBL6026583 | 0.91 | NR1H4 (0.47) | NR1H4ELANE | |
| SCHEMBL4615585 | 0.91 | NR1H4 (0.46) | NR1H4ELANE | |
| SCHEMBL5709130 | 0.90 | NR1H4 (0.55) | NR1H4KMT2AATMELANE | |
| SCHEMBL4659695 | 0.90 | NR1H4 (0.41) | NR1H4ELANE | |
| SCHEMBL5706924 | 0.90 | NR1H4 (0.56) | NR1H4KMT2AATMELANE | |
| SCHEMBL5709066 | 0.90 | NR1H4 (0.56) | NR1H4KMT2AATMELANE | |
| SCHEMBL6256758 | 0.89 | NR1H4 (0.50) | NR1H4KMT2AATMELANE | |
| SCHEMBL14677996 | 0.89 | NR1H4 (0.48) | NR1H4KMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877067-A1 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONE GLUCURONIDE DERIVATIVES FOR HYPERCHOLESTEROLEMIA | Microbia, Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006116499-A1 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONE GLUCURONIDE DERIVATIVES FOR HYPERCHOLESTEROLEMIA | MICROBIA, INC. (US) | 2006-11-02 | — | — | WO | disclosed |
| EP-1610770-A1 | USE OF AN IBAT INHIBITOR FOR THE TREATMENT OF PROPHYLAXIS OF CONSTIPATION | AstraZeneca AB (SE) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004089350-A1 | USE OF AN IBAT INHIBITOR FOR THE TREATMENT OF PROPHYLAXIS OF CONSTIPATION | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | disclosed |