Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.67 |
| ▸ | BCR | P11274 | 2/20 | 0.67 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22458668 | 0.88 | ABL1 (0.70) | ABL1BCRCLK4CYP1A2CYP2C9 | |
| SCHEMBL4666050 | 0.87 | ABL1 (0.71) | ABL1BCRCLK4CYP1A2CYP2C9 | |
| SCHEMBL4117227 | 0.86 | ABL1 (0.68) | ABL1BCRCLK4CYP1A2CYP2C9 | |
| SCHEMBL4103908 | 0.85 | ABL1 (0.65) | ABL1BCRCLK4CYP1A2CYP2C9 | |
| SCHEMBL4101900 | 0.84 | ABL1 (0.60) | ABL1BCRCLK4CYP1A2CYP2C9 | |
| SCHEMBL4104093 | 0.84 | ABL1 (0.64) | ABL1BCRCLK4CYP1A2CYP2C9 | |
| SCHEMBL4109254 | 0.84 | ABL1 (0.74) | ABL1BCRMAPTKDM4EMAPK1 | |
| SCHEMBL1242053 | 0.83 | ADORA3 (0.57) | ABL1BCRCLK4CYP1A2CYP2C9 | |
| SCHEMBL2305280 | 0.82 | TP53 (0.74) | ABL1BCRCLK4CYP1A2CYP2C9 | |
| SCHEMBL4108187 | 0.82 | ABL1 (0.54) | ABL1BCRCLK4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | ABL1 24/4885BCR 402/4885CLK4 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.