Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025313 | 0.95 | PPARD (0.41) | FFAR1FFAR4PPARDPPARACTSS | |
| SCHEMBL19294595 | 0.95 | PPARD (0.41) | FFAR1FFAR4PPARDPPARACTSS | |
| SCHEMBL19294596 | 0.86 | FFAR1 (0.55) | FFAR1FFAR4PPARDLMNAL3MBTL1 | |
| SCHEMBL3580780 | 0.86 | FFAR1 (0.55) | FFAR1FFAR4PPARDLMNAL3MBTL1 | |
| SCHEMBL18741368 | 0.83 | MEN1 (0.40) | FFAR1PPARANR1H2NR1H3MEN1 | |
| SCHEMBL18741285 | 0.83 | MTNR1A (0.34) | FFAR1PPARANR1H2NR1H3 | |
| SCHEMBL3590948 | 0.83 | TDP1 (0.49) | FFAR1CTSSCTSKL3MBTL1MEN1 | |
| SCHEMBL17593417 | 0.82 | PPARD (0.41) | FFAR1FFAR4PPARDPPARACTSS | |
| SCHEMBL18741306 | 0.82 | KCNH2 (0.41) | FFAR1PPARDPPARALMNAL3MBTL1 | |
| SCHEMBL20025317 | 0.82 | PPARA (0.40) | PPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915354-A1 | NOVEL BENZOTHIAZOLONE DERIVATIVES | AstraZeneca AB (SE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007018461-A1 | NOVEL BENZOTHIAZOLONE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | disclosed |