Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127446 | 0.83 | EGFR (0.41) | EGFRERBB2MEN1KMT2AADRB2 | |
| SCHEMBL4127445 | 0.77 | EGFR (0.45) | EGFRERBB2MEN1KMT2AADRB2 | |
| SCHEMBL4120978 | 0.76 | EGFR (0.48) | EGFRERBB2MEN1KMT2AADRB2 | |
| SCHEMBL4120979 | 0.76 | EGFR (0.48) | EGFRERBB2MEN1KMT2AADRB2 | |
| SCHEMBL4138368 | 0.73 | EGFR (0.42) | EGFRERBB2MEN1KMT2AADRB2 | |
| SCHEMBL4138363 | 0.73 | EGFR (0.42) | EGFRERBB2MEN1KMT2AADRB2 | |
| SCHEMBL4122971 | 0.69 | EGFR (0.45) | EGFRERBB2MEN1KMT2AADRB2 | |
| SCHEMBL4137534 | 0.69 | ALOX5 (0.52) | EGFRERBB2MEN1KMT2A | |
| SCHEMBL4137539 | 0.69 | ALOX5 (0.52) | EGFRERBB2MEN1KMT2A | |
| SCHEMBL4139742 | 0.69 | EGFR (0.45) | EGFRERBB2MEN1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |