Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666522 | 0.92 | KDM4C (0.43) | ALDH1A1KDM4EMAPTTP53GFER | |
| SCHEMBL4665751 | 0.87 | HPGD (0.43) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL14600210 | 0.85 | DHODH (0.45) | MAPTTP53ADORA1 | |
| SCHEMBL14600476 | 0.85 | KDM4C (0.43) | ALDH1A1KDM4EMAPTTP53GFER | |
| SCHEMBL14600212 | 0.84 | KDM4C (0.38) | ALDH1A1KDM4EMAPTTP53ADORA1 | |
| SCHEMBL14600664 | 0.80 | HPGD (0.44) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL4668570 | 0.79 | GFER (0.42) | KDM4EMAPTKMT2ATP53GFER | |
| SCHEMBL14600270 | 0.78 | GFER (0.42) | MAPTKMT2ATP53GFERADORA1 | |
| SCHEMBL14600268 | 0.78 | ADORA1 (0.42) | MAPTTP53GFERADORA1 | |
| Hydrochloric Acid SCHEMBL4669539 | 0.78 | GFER (0.41) | KDM4EMAPTKMT2ATP53GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |