Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 2/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600476 | 0.93 | KDM4C (0.43) | KDM4CADORA1MAPTTP53KDM4E | |
| SCHEMBL4666599 | 0.92 | ALDH1A1 (0.41) | ADORA1MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL14600210 | 0.91 | DHODH (0.45) | KDM4CADORA1MAPTTP53FABP4 | |
| SCHEMBL14600212 | 0.90 | KDM4C (0.38) | KDM4CADORA1MAPTTP53KDM4E | |
| SCHEMBL4668570 | 0.86 | GFER (0.42) | KDM4CADORA1MAPTTP53KDM4E | |
| SCHEMBL14600268 | 0.86 | ADORA1 (0.42) | ADORA1MAPTTP53GFERFABP4 | |
| SCHEMBL14600270 | 0.86 | GFER (0.42) | ADORA1MAPTTP53GFERFABP4 | |
| Hydrochloric Acid SCHEMBL4669539 | 0.86 | GFER (0.41) | KDM4CADORA1MAPTTP53KDM4E | |
| SCHEMBL14600211 | 0.85 | ADORA1 (0.43) | ADORA1MAPTTP53ALDH1A1GFER | |
| SCHEMBL14600717 | 0.83 | ADORA1 (0.43) | ADORA1MAPTTP53ALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |