SCHEMBL4666835

SCHEMBL4666835

NC(=O)[C@@H]1Cc2ccccc2CN1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SCN3A Q9NY46 1/20 0.52
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
PRCP P42785 1/20 0.46
SMYD3 Q9H7B4 1/20 0.45
PNMT P11086 4/20 0.44
OPRM1 P35372 1/20 0.44
OPRD1 P41143 1/20 0.44
OPRK1 P41145 1/20 0.44
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29474880 1.00 SCN3A (0.52) SCN3AMEN1KMT2APRCPSMYD3
SCHEMBL32677003 1.00 SCN3A (0.52) SCN3AMEN1KMT2APRCPSMYD3
SCHEMBL32677100 1.00 SCN3A (0.52) SCN3AMEN1KMT2APRCPSMYD3
SCHEMBL1509610 1.00 SCN3A (0.52) SCN3AMEN1KMT2APRCPSMYD3
Hydrochloric Acid SCHEMBL30225627 0.98 MEN1 (0.51) SCN3AMEN1KMT2APRCPSMYD3
Hydrochloric Acid SCHEMBL29897791 0.98 MEN1 (0.51) SCN3AMEN1KMT2APRCPSMYD3
Hydrochloric Acid SCHEMBL27787267 0.98 MEN1 (0.51) SCN3AMEN1KMT2APRCPSMYD3
Hydrochloric Acid SCHEMBL4787147 0.98 MEN1 (0.51) SCN3AMEN1KMT2APRCPSMYD3
SCHEMBL288272 0.83 GAA (0.58) MEN1KMT2APRCPPNMTOPRM1
SCHEMBL288260 0.83 GAA (0.58) MEN1KMT2APRCPPNMTOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1416933-B8 SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEN INC (US) 2008-08-27 EP claimed
EP-1416933-B1 SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEM INC (US) 2008-01-02 EP claimed
US-20070265248-A1 Substituted piperazines and methods of use AMGEN INC. (US) 2007-11-15 US claimed
EP-0751128-B2 Process for producing optically active amides AJINOMOTO KK (JP) 2005-08-31 EP claimed
EP-1416933-A1 SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR Amgem, Inc. (US) 2004-05-12 EP claimed
WO-2003009847-A1 SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEM, INC. (US) 2003-02-06 WO claimed
EP-0751128-B1 Process for producing optically active amides AJINOMOTO KK (JP) 1999-07-28 EP claimed
EP-0751128-A1 Process for producing optically active amides Ajinomoto Co., Ltd. (JP) 1997-01-02 EP claimed
US-12503455-B2 Nucleic acid-binding photoprobes and uses thereof ARRAKIS THERAPEUTICS, INC. (US) 2025-12-23 US disclosed
US-11807623-B2 Nucleic acid-binding photoprobes and uses thereof ARRAKIS THERAPEUTICS, INC. (US) 2023-11-07 US disclosed
US-20230312520-A1 NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF ARRAKIS THERAPEUTICS, INC. 2023-10-05 US disclosed
US-20220009903-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2022-01-13 US disclosed
EP-3717009-A1 NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF Arrakis Therapeutics, Inc. (US) 2020-10-07 EP disclosed
CN-111386127-A Nucleic acid-binding light probes and uses thereof 阿拉基斯医疗公司 2020-07-07 CN disclosed
US-5994545-A TETRAHYDROISOQUINOLINE-3(S)-CARBOXYLIC ACID N-CARBOXY ANHYDRIDE; INTERMEDIATES OF SAQUINAVIR (EP 432694). AJINOMOTO CO., INC. (JP) 1999-11-30 US disclosed
US-5994545-A TETRAHYDROISOQUINOLINE-3(S)-CARBOXYLIC ACID N-CARBOXY ANHYDRIDE; INTERMEDIATES OF SAQUINAVIR (EP 432694). AJINOMOTO CO., INC. (JP) 1999-11-30 US disclosed
EP-0751128-B1 Process for producing optically active amides AJINOMOTO KK (JP) 1999-07-28 EP disclosed
WO-1999028313-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1999-06-10 WO disclosed
EP-0751128-A1 Process for producing optically active amides Ajinomoto Co., Ltd. (JP) 1997-01-02 EP disclosed
EP-0751128-A1 Process for producing optically active amides Ajinomoto Co., Ltd. (JP) 1997-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312520-A1 NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF NSUN3, NSUN2, TARBP1 SCN3A 4664/4885MEN1 4474/4885KMT2A 2159/4885
US-20070265248-A1 Substituted piperazines and methods of use MC5R, MC4R, MC1R SCN3A 1706/4885MEN1 1339/4885KMT2A 1330/4885
US-12503455-B2 Nucleic acid-binding photoprobes and uses thereof NSUN3, NSUN2, TARBP1 SCN3A 4664/4885MEN1 4474/4885KMT2A 2159/4885
US-20220009903-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 SCN3A 1459/4885MEN1 1494/4885KMT2A 4121/4885
US-11807623-B2 Nucleic acid-binding photoprobes and uses thereof NSUN3, NSUN2, TARBP1 SCN3A 4664/4885MEN1 4474/4885KMT2A 2159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.