Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 17/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.45 |
| ▸ | DRD2 | P14416 | 14/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555050 | 1.00 | DRD3 (0.45) | DRD3KCNH2DRD2CYP1A2DRD4 | |
| SCHEMBL13312904 | 1.00 | DRD3 (0.45) | DRD3KCNH2DRD2CYP1A2DRD4 | |
| SCHEMBL3623998 | 1.00 | DRD3 (0.45) | DRD3KCNH2DRD2CYP1A2DRD4 | |
| SCHEMBL12809870 | 0.90 | DRD3 (0.44) | DRD3KCNH2DRD2CYP1A2DRD4 | |
| SCHEMBL14567571 | 0.90 | DRD3 (0.44) | DRD3KCNH2DRD2CYP1A2DRD4 | |
| SCHEMBL378256 | 0.83 | DRD3 (0.55) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL13089084 | 0.83 | DRD3 (0.55) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL379237 | 0.83 | POLB (0.41) | DRD3KCNH2DRD2 | |
| SCHEMBL12313188 | 0.83 | POLB (0.41) | DRD3KCNH2DRD2 | |
| SCHEMBL11911752 | 0.83 | POLB (0.41) | DRD3KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926723-A2 | AZABICYCLO (3,1,0) HEXAN DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RCEPTORS | GLAXO GROUP LIMITED (GB) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007022934-A2 | AZABICYCLO (3, 1, 0) HEXAN DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2007-03-01 | — | — | WO | disclosed |