Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 11/20 | 0.40 |
| ▸ | TACR2 | P21452 | 8/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665925 | 1.00 | TACR3 (0.40) | TACR3TACR2OPRM1L3MBTL1ALDH1A1 | |
| SCHEMBL4665218 | 0.93 | TACR3 (0.44) | TACR3TACR2OPRM1L3MBTL1ALDH1A1 | |
| SCHEMBL4667068 | 0.92 | TACR3 (0.41) | TACR3TACR2OPRM1LMNAKCNH2 | |
| SCHEMBL4667024 | 0.87 | AGER (0.40) | TACR3TACR2OPRM1ALDH1A1LMNA | |
| SCHEMBL4665287 | 0.86 | FNTA (0.39) | TACR3ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4665277 | 0.84 | TSHR (0.46) | TACR3TACR2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL4665272 | 0.83 | TSHR (0.47) | TACR3TACR2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL4667460 | 0.81 | MEN1 (0.42) | TACR3OPRM1MEN1KMT2A | |
| SCHEMBL4665269 | 0.80 | TACR3 (0.42) | TACR3TACR2KCNH2 | |
| SCHEMBL4667560 | 0.80 | MEN1 (0.43) | TACR3OPRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940795-A1 | N-OXO-HETEROCYCLE AND N-OXO-ALKYL QUINOLINE-4-CARBOXAMIDES AS NK-3 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2008-07-09 | — | — | EP | claimed |
| WO-2007035156-A1 | N-OXO-HETEROCYCLE AND N-OXO-ALKYL QUINOLINE-4-CARBOXAMIDES AS NK-3 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2007-03-29 | — | — | WO | claimed |