SCHEMBL466709

SCHEMBL466709

C/C=C/CCCCN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16056 1.00
SCHEMBL11740831 1.00
SCHEMBL466607 0.97 DNM1 (0.44)
SCHEMBL466635 0.97
SCHEMBL467030 0.97 DNM1 (0.44)
SCHEMBL24243667 0.97 DNM1 (0.44)
SCHEMBL467031 0.97 DNM1 (0.44)
SCHEMBL9556261 0.97 DNM1 (0.44)
SCHEMBL20859604 0.97 DNM1 (0.44)
SCHEMBL7909548 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses ALCON INC. (CH) 2023-02-21 US claimed
US-20200376787-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2020-12-03 US claimed
WO-2020240440-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2020-12-03 WO claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US disclosed
US-12297323-B2 Polysiloxane vinylic crosslinkers with high refractive index ALCON INC. (CH) 2025-05-13 US disclosed
EP-4314118-B1 POLYSILOXANE VINYLIC CROSSLINKERS WITH HIGH REFRACTIVE INDEX ALCON INC (CH) 2025-04-30 EP disclosed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 US disclosed
US-20250059330-A1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-02-20 US disclosed
EP-4481478-A2 SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-12-25 EP disclosed
US-12162987-B2 Silicone hydrogel contact lenses ALCON INC. (CH) 2024-12-10 US disclosed
EP-4235274-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-10-09 EP disclosed
US-8877857-B2 Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-11-04 US disclosed
EP-2404944-B1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE SUMITOMO RUBBER IND (JP) 2014-05-14 EP disclosed
CN-102365306-B Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER IND 2014-04-02 CN disclosed
US-20120095153-A1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-04-19 US disclosed
CN-102365306-A Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER IND 2012-02-29 CN disclosed
EP-2404944-A1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE Sumitomo Rubber Industries, Ltd. (JP) 2012-01-11 EP disclosed
US-4064259-A Thiazole cardiovascular agents SYNTEX (U.S.A.) INC. (US) 1977-12-20 US disclosed
US-4064135-A Certain thiazole-5-carboxamide compounds SYNTEX (U.S.A.) INC. (US) 1977-12-20 US disclosed