SCHEMBL466743

SCHEMBL466743

CC(CN)C1=CCCCC1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.34
KDM1A O60341 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20290520 0.98 TAAR1 (0.33) TAAR1KDM1ASMN1; SMN2
SCHEMBL4744556 0.81 KMT2A (0.33) SMN1; SMN2
SCHEMBL27014984 0.81
SCHEMBL27610746 0.79 SMN1; SMN2 (0.34) SMN1; SMN2
SCHEMBL27495171 0.79 SMN1; SMN2 (0.34) SMN1; SMN2
SCHEMBL7994426 0.79 KMT2A (0.33) SMN1; SMN2
SCHEMBL8125749 0.79 KMT2A (0.33) SMN1; SMN2
SCHEMBL5077494 0.79 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL10338316 0.78 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL7994447 0.78 SMN1; SMN2 (0.30) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877857-B2 Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-11-04 US disclosed
EP-2404944-B1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE SUMITOMO RUBBER IND (JP) 2014-05-14 EP disclosed
CN-102365306-B Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER IND 2014-04-02 CN disclosed
US-20120095153-A1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-04-19 US disclosed
CN-102365306-A Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER IND 2012-02-29 CN disclosed
EP-2404944-A1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE Sumitomo Rubber Industries, Ltd. (JP) 2012-01-11 EP disclosed