SCHEMBL5077494

SCHEMBL5077494

[CH2]CC(C)C1=CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7994447 0.98 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL7994444 0.98 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL7994499 0.94
SCHEMBL4744556 0.81 KMT2A (0.33) SMN1; SMN2
SCHEMBL466743 0.79 TAAR1 (0.34) SMN1; SMN2
SCHEMBL8125749 0.79 KMT2A (0.33) SMN1; SMN2
SCHEMBL7994426 0.79 KMT2A (0.33) SMN1; SMN2
SCHEMBL2701925 0.79
SCHEMBL20290520 0.78 TAAR1 (0.33) SMN1; SMN2
SCHEMBL10338316 0.78 SMN1; SMN2 (0.33) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255121-A1 Combination Drug for Treating Autoimmune Disease DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2008-10-16 US disclosed
EP-1815867-A1 COMBINATION DRUG FOR TREATING AUTOIMMUNE DISEASE Dainippon Sumitomo Pharma Co., Ltd. (JP) 2007-08-08 EP disclosed
EP-0979226-B1 ISOXAZOLE DERIVATIVES SUMITOMO PHARMA (JP) 2005-11-09 EP disclosed
EP-1201661-A1 HETEROAROMATIC RING COMPOUNDS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2002-05-02 EP disclosed
US-6277790-B1 APPLYING PLANTS, SEEDS, SOILS OR ENVIRONMENT BASF AKTIENGESELLSCHAFT (DE) 2001-08-21 US disclosed
US-6100260-A ((3-(1-(2-FLUORO-BIPHENYL-4-YL)-ETHYL)-ISOXAZOL-5-YLIMINO) -MORPHOLIN-4-YL-M ETHYL)-AMINE, FOR EXAMPLE; ADMINISTERING TO TREAT AUTOIMMUNE DISEASES AND INFLAMMATION SUMITOMO PHARMACEUTICAL COMPANY, LIMITED (JP) 2000-08-08 US disclosed
EP-0979226-A1 ISOXAZOLE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2000-02-16 EP disclosed
WO-1998047880-A1 ISOXAZOLE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1998-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080255121-A1 Combination Drug for Treating Autoimmune Disease CAMK2D, CAMK2G, CAMK2B SMN1; SMN2 3341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.