Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600248 | 0.93 | DHODH (0.38) | NTRK1LMNATP53MAPTDHODH | |
| SCHEMBL14600468 | 0.85 | DHODH (0.40) | LMNATP53MAPTDHODHALDH1A1 | |
| SCHEMBL4668579 | 0.85 | F2 (0.35) | NTRK1LMNATP53MAPTF2 | |
| SCHEMBL14600465 | 0.84 | DHODH (0.46) | TP53MAPTDHODHADORA1 | |
| SCHEMBL14600717 | 0.84 | ADORA1 (0.43) | LMNATP53MAPTDHODHALDH1A1 | |
| SCHEMBL14600722 | 0.83 | SORT1 (0.41) | LMNATP53MAPTDHODHALDH1A1 | |
| SCHEMBL14600466 | 0.83 | ADORA1 (0.42) | LMNATP53MAPTDHODHALDH1A1 | |
| SCHEMBL14600467 | 0.83 | DHODH (0.41) | TP53DHODHADORA1 | |
| SCHEMBL14600214 | 0.82 | DHODH (0.44) | NTRK1LMNADHODHALDH1A1 | |
| SCHEMBL14600469 | 0.82 | NTRK1 (0.44) | NTRK1DHODHF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |