Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 3/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667558 | 0.90 | FFAR1 (0.48) | FFAR1SCN1ASCN2ASCN3ASLC6A2 | |
| SCHEMBL5160316 | 0.90 | SLC6A2 (0.52) | FFAR1SLC6A2SLC6A4SLC6A3KCNH2 | |
| Formamide SCHEMBL5161701 | 0.85 | SLC6A2 (0.48) | FFAR1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL11054725 | 0.82 | ACP3 (0.53) | SLC6A2SLC6A4SLC6A3LMNATSHR | |
| SCHEMBL4667564 | 0.82 | SCN1A (0.65) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| SCHEMBL5163408 | 0.82 | ACP3 (0.43) | FFAR1SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL4667569 | 0.79 | GAA (0.46) | FFAR1MEN1CYP3A4CYP2C9ALOX15 | |
| SCHEMBL4667575 | 0.79 | CYP2D6 (0.58) | SLC6A2SLC6A4SLC6A3TSHRKCNH2 | |
| SCHEMBL11813722 | 0.76 | SCN1A (0.46) | SCN1ASCN2ASCN3ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5269207 | 0.76 | FFAR1 (0.44) | FFAR1IDO1TDO2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930308-A1 | Pharmaceutical agents for the treatment of cerebral amyloidosis | NYMOX CORPORATION (CA) | 2008-06-11 | — | — | EP | disclosed |
| EP-0983222-B1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 2007-11-28 | — | — | EP | disclosed |
| US-6518314-B1 | For treating cerebral amyloidosis; compounds that impede the transformation of dense microspheres (DMS) into amyloid | NYMOX CORPORATION (CA) | 2003-02-11 | — | — | US | disclosed |
| US-6130221-A | ALZHEIMERS | NYMOX CORPORATION (CA) | 2000-10-10 | — | — | US | disclosed |
| EP-0983222-A1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORPORATION (CA) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052898-A1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORPORATION (CA) | 1998-11-26 | — | — | WO | disclosed |