⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722836 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL8722818 | 0.97 | GRIK1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL8722822 | 0.97 | GRIK1 (0.36) | — | |
| SCHEMBL27261001 | 0.83 | — | — | |
| SCHEMBL22068150 | 0.79 | — | — | |
| SCHEMBL20732058 | 0.78 | — | — | |
| SCHEMBL24106547 | 0.77 | GRIK1 (0.34) | — | |
| SCHEMBL466778 | 0.77 | — | — | |
| SCHEMBL466779 | 0.77 | — | — | |
| SCHEMBL17192605 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334194-A | 3- (5-amino-1-oxoisoindolin-2-yl) piperidine-2, 6-dione derivatives and their use in the treatment of IKAROS family Zinc finger 2(IKZF2) dependent diseases | 诺华股份有限公司 | 2021-02-05 | — | — | CN | disclosed |
| US-5783169-A | RADIOIMMUNOCONJUGATED; DIAGNOSTIC AND THERAPY | BROOKHAVEN SCIENCE ASSOCIATES LLC (US) | 1998-07-21 | — | — | US | disclosed |