⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671396 | 1.00 | — | — | |
| SCHEMBL3381251 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL4669861 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL4669857 | 0.97 | — | — | |
| SCHEMBL29054582 | 0.84 | — | — | |
| SCHEMBL29054583 | 0.84 | — | — | |
| SCHEMBL2193910 | 0.82 | LMNA (0.50) | — | |
| SCHEMBL28070224 | 0.78 | — | — | |
| SCHEMBL10943349 | 0.77 | — | — | |
| SCHEMBL628995 | 0.77 | LMNA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193253-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AZETIDINE-2-CARBOXYLIC ACIDS | KANEKA CORP (JP) | 2008-06-25 | — | — | EP | disclosed |
| EP-1927588-A2 | Process for producing optically active azetidine-2-carboxylic acids | KANEKA CORPORATION (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-7262308-B2 | Process for producing optically active azetidine-2-carboxylic acids | KANEKA CORPORATION (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20050043547-A1 | Process for producing optically active azetidine-2-carboxylic acids | HONDA TATSUYA (JP) | 2005-02-24 | — | — | US | disclosed |
| EP-1253140-B1 | PROCESS FOR CYCLIZING OPTICALLY ACTIVE 4-AMINO-2-HALOGENOBUTYRIC ACIDS | KANEKA CORP (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6838567-B1 | Process for producing optically active azetidine-2-carboxylic acids | KANEKA CORPORATION (JP) | 2005-01-04 | — | — | US | disclosed |
| US-20040171849-A1 | Process for producing optically active azetidine-2-carboxylic acid | KANEKA CORPORATION (JP) | 2004-09-02 | — | — | US | disclosed |
| US-6747161-B2 | AZETIDINE-2-CARBOXYLIC ACID; ALKALINE EARTH METAL OXIDE OR HYDROXIDE, OR AMINE; HIGH OPTICAL YIELD | KANEKA CORPORATION (JP) | 2004-06-08 | — | — | US | disclosed |
| EP-1415985-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AZETIDINE-2-CARBOXYLIC ACID | KANEKA CORPORATION (JP) | 2004-05-06 | — | — | EP | disclosed |
| EP-1170287-B1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE N-SUBSTITUTED AZETIDINE-2-CARBOXYLIC ACIDS | KANEKA CORP (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6617461-B2 | Cyclizing an optically active 4-substituted amino-2-halobutyric acid containing substituted oxycarbonyl or sulfonyl type protective group in presence of a base | KANEKA CORPORATION (JP) | 2003-09-09 | — | — | US | disclosed |
| US-20030109719-A1 | Process for cyclizing optically active 4-amino-2-halogenobutyric acids | SAKA YASUHIRO (JP) | 2003-06-12 | — | — | US | disclosed |
| US-20030045730-A1 | Process for preparation of optically active n-substituted azetidine-2-carboxylic acids | KANEKA CORPORATION (JP) | 2003-03-06 | — | — | US | disclosed |
| EP-1253140-A1 | PROCESS FOR CYCLIZING OPTICALLY ACTIVE 4-AMINO-2-HALOGENOBUTYRIC ACIDS | KANEKA CORPORATION (JP) | 2002-10-30 | — | — | EP | disclosed |
| EP-1193253-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AZETIDINE-2-CARBOXYLIC ACIDS | KANEKA CORPORATION (JP) | 2002-04-03 | — | — | EP | disclosed |
| EP-1170287-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE N-SUBSTITUTED AZETIDINE-2-CARBOXYLIC ACIDS | KANEKA CORPORATION (JP) | 2002-01-09 | — | — | EP | disclosed |