Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 14/20 | 0.42 |
| ▸ | PGR | P06401 | 13/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | GYS1 | P13807 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564457 | 0.76 | NR3C1 (0.54) | NR3C1NR3C2PGRPARP1PTGS1 | |
| SCHEMBL4668326 | 0.74 | NR3C1 (0.44) | NR3C1NR3C2PGRPARP1PTGS1 | |
| SCHEMBL1635036 | 0.72 | PARP1 (0.48) | NR3C1NR3C2PGRPARP1PTGS1 | |
| SCHEMBL14081359 | 0.71 | NR3C1 (0.62) | NR3C1NR3C2PGRPARP1PTGS1 | |
| SCHEMBL1775739 | 0.71 | NR3C2 (0.48) | NR3C1NR3C2 | |
| SCHEMBL14081376 | 0.71 | NR3C1 (0.59) | NR3C1NR3C2PGRPARP1PTGS1 | |
| SCHEMBL3957430 | 0.70 | NR3C1 (0.51) | NR3C1NR3C2PGRPARP1PTGS1 | |
| SCHEMBL14189079 | 0.70 | NR3C1 (0.48) | NR3C1NR3C2PGRPARP1PTGS1 | |
| SCHEMBL563723 | 0.69 | NR3C1 (0.62) | NR3C1NR3C2PGRPARP1PTGS1 | |
| SCHEMBL3690152 | 0.69 | NR3C1 (0.57) | NR3C1NR3C2PGRPARP1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982976-A1 | Process for the manufacture of non-steroidal anti-inflammatory agents and intermediates thereof | Intendis GmbH (DE) | 2008-10-22 | — | — | EP | disclosed |