Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668793 | 1.00 | CCR2 (0.56) | CCR2MEN1KMT2AOPRK1SIGMAR1 | |
| SCHEMBL3869696 | 0.95 | CCR2 (0.59) | CCR2MEN1KMT2A | |
| SCHEMBL3869699 | 0.95 | CCR2 (0.59) | CCR2MEN1KMT2A | |
| SCHEMBL13853132 | 0.93 | MEN1 (0.63) | CCR2MEN1KMT2AOPRK1 | |
| SCHEMBL3879508 | 0.93 | MEN1 (0.63) | CCR2MEN1KMT2AOPRK1 | |
| SCHEMBL3869069 | 0.89 | CCR2 (0.69) | CCR2MEN1KMT2AOPRK1 | |
| SCHEMBL3869073 | 0.89 | CCR2 (0.69) | CCR2MEN1KMT2AOPRK1 | |
| SCHEMBL3870197 | 0.89 | CCR2 (0.69) | CCR2MEN1KMT2AOPRK1 | |
| SCHEMBL3869044 | 0.85 | CCR2 (0.59) | CCR2MEN1KMT2AOPRK1 | |
| SCHEMBL3869049 | 0.85 | CCR2 (0.59) | CCR2MEN1KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891064-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | Laboratorios Almirall, S.A. (ES) | 2008-02-27 | — | — | EP | claimed |
| WO-2006133802-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-12-21 | — | — | WO | claimed |
| EP-1891064-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | Laboratorios Almirall, S.A. (ES) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006133802-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-12-21 | — | — | WO | disclosed |