SCHEMBL4668960

SCHEMBL4668960

CNc1cc(O)c(NC(=O)O)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 2/20 0.38
FTO Q9C0B1 1/20 0.38
POLB P06746 2/20 0.37
RAB9A P51151 1/20 0.36
GAA P10253 4/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 2/20 0.36
GPR35 Q9HC97 1/20 0.36
KCNMA1 Q12791 3/20 0.35
TRPV1 Q8NER1 1/20 0.35
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4667381 0.84 ALDH1A1 (0.44) CXCR2FTOPOLBRAB9AGAA
SCHEMBL4669248 0.84 ALDH1A1 (0.40) CXCR2FTORAB9AGAAKMT2A
SCHEMBL7250153 0.83 HPGD (0.42) RAB9AGAAKMT2AALDH1A1MAPT
SCHEMBL4667415 0.81 APEX1 (0.45) CXCR2POLBRAB9AALDH1A1CA1
SCHEMBL7253209 0.81 ALDH1A1 (0.55) POLBKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL4669092 0.79 KDR (0.41) CXCR2GAAKMT2AMAPTSMN1; SMN2
SCHEMBL4667980 0.79 MAPK1 (0.55) CXCR2GAAKMT2AMAPTSMN1; SMN2
SCHEMBL4668862 0.78 ABCC1 (0.42) POLBRAB9AGAASMN1; SMN2TRPV1
SCHEMBL7251605 0.78 HPGD (0.44) RAB9AGAAKMT2AMAPTSMN1; SMN2
SCHEMBL28391741 0.77 HPGD (0.46) FTOPOLBGAAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1129689-B1 Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing OREAL (FR) 2008-07-09 EP claimed