Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668704 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EGLAGAANR1H2 | |
| SCHEMBL4668038 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL4669179 | 0.74 | CYP3A4 (0.43) | ALDH1A1KDM4EGAAMAPK1MAPT | |
| SCHEMBL988555 | 0.72 | TSHR (0.59) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL4667384 | 0.71 | TSHR (0.41) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL972928 | 0.69 | SRD5A2 (0.48) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL11815093 | 0.69 | APEX1 (0.45) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL16281303 | 0.68 | PRKCI (0.62) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL988434 | 0.68 | LRRK2 (0.48) | ALDH1A1KDM4EGLAGAASMN1; SMN2 | |
| SCHEMBL6129408 | 0.68 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129689-B1 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | OREAL (FR) | 2008-07-09 | — | — | EP | claimed |