⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866058 | 0.79 | — | — | |
| SCHEMBL2495953 | 0.79 | — | — | |
| SCHEMBL17579578 | 0.72 | ALDH1A1 (0.31) | — | |
| SCHEMBL610641 | 0.72 | ALDH1A1 (0.31) | — | |
| SCHEMBL1482677 | 0.72 | — | — | |
| SCHEMBL54548 | 0.72 | ALDH1A1 (0.31) | — | |
| SCHEMBL139829 | 0.70 | — | — | |
| SCHEMBL11374254 | 0.70 | — | — | |
| SCHEMBL14338115 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL2638646 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931767-B1 | AMPHIPHILIC SILOXANE-CONTAINING (METH)ACRYLAMIDES AND USES THEREOF | NOVARTIS AG (CH) | 2017-11-08 | — | — | EP | disclosed |
| US-9268064-B2 | Amphiphilic siloxane-containing (meth)acrylamides and uses thereof | NOVARTIS AG (CH) | 2016-02-23 | — | — | US | disclosed |
| US-20150301228-A1 | AMPHIPHILIC SILOXANE-CONTAINING (METH)ACRYLAMIDES AND USES THEREOF | ALCON INC. (CH) | 2015-10-22 | — | — | US | disclosed |
| EP-2931767-A1 | AMPHIPHILIC SILOXANE-CONTAINING (METH)ACRYLAMIDES AND USES THEREOF | Novartis AG (CH) | 2015-10-21 | — | — | EP | disclosed |
| US-9097840-B2 | Amphiphilic siloxane-containing (meth)acrylamides and uses thereof | NOVARTIS AG (CH) | 2015-08-04 | — | — | US | disclosed |
| US-20140171539-A1 | AMPHIPHILIC SILOXANE-CONTAINING (METH)ACRYLAMIDES AND USES THEREOF | NOVARTIS AG (CH) | 2014-06-19 | — | — | US | disclosed |
| WO-2014093764-A1 | AMPHIPHILIC SILOXANE-CONTAINING (METH)ACRYLAMIDES AND USES THEREOF | NOVARTIS AG (CH) | 2014-06-19 | — | — | WO | disclosed |
| EP-1894936-A1 | Organosilyl-Benzo-triazole derivatives, processes for their production and their use as UV protecting agents | ISDIN, S.A. (ES) | 2008-03-05 | — | — | EP | disclosed |