Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | TDO2 | P48775 | 2/20 | 0.50 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974763 | 0.91 | IDO1 (0.46) | IDO1TDO2SCN4ACHRNA7DRD3 | |
| SCHEMBL10965879 | 0.88 | SCN4A (0.45) | IDO1TDO2SCN4ACHRNA7DRD3 | |
| SCHEMBL7129055 | 0.78 | HTR2A (0.50) | SCN4ATSHRHRH1HTR2ATACR1 | |
| SCHEMBL14269139 | 0.78 | ALDH1A1 (0.42) | OPRM1HRH1HTR2AOPRK1TDP1 | |
| SCHEMBL7956378 | 0.75 | HSD17B10 (0.41) | DRD3KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5190981 | 0.73 | CYP3A4 (0.64) | IDO1TDO2DRD3KCNH2SLC6A2 | |
| SCHEMBL4669314 | 0.73 | CYP3A4 (0.64) | IDO1TDO2DRD3KCNH2SLC6A2 | |
| SCHEMBL1979244 | 0.72 | HTR2A (0.73) | IDO1TDO2SCN4ACHRNA7DRD3 | |
| SCHEMBL7429108 | 0.72 | IDO1 (0.50) | IDO1TDO2SCN4ACHRNA7DRD3 | |
| SCHEMBL21068075 | 0.72 | HTR2A (0.73) | IDO1TDO2SCN4ACHRNA7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930308-A1 | Pharmaceutical agents for the treatment of cerebral amyloidosis | NYMOX CORPORATION (CA) | 2008-06-11 | — | — | EP | disclosed |