Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14237605 | 0.77 | KMT2A (0.30) | LMNATP53CYP1A2CYP3A4ALOX15 | |
| SCHEMBL3380118 | 0.76 | HMGCR (0.50) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL6944051 | 0.75 | — | — | |
| SCHEMBL1281746 | 0.73 | TSHR (0.36) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL1281745 | 0.73 | TSHR (0.36) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL125115 | 0.71 | — | — | |
| SCHEMBL16280996 | 0.71 | KDM4E (0.42) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL23771993 | 0.70 | — | — | |
| SCHEMBL5105686 | 0.70 | KDM4E (0.33) | KDM4EGMNNUSP2ALDH1A1LMNA | |
| SCHEMBL1133260 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403856-B1 | METHYLENEDIOXYBENZO [I]PHENANTHRIDINE DERIVATIVES USED TO TREAT CANCER | UNIV RUTGERS (US) | 2012-12-19 | — | — | EP | claimed |
| EP-1721713-B1 | Methods and product for enhancing penetration of wood preservatives | LONZA AG (US) | 2008-04-30 | — | — | EP | disclosed |
| EP-1721713-A1 | Methods and product for enhancing penetration of wood preservatives | LONZA, INC. (US) | 2006-11-15 | — | — | EP | disclosed |
| US-6485790-B2 | BY ALSO APPLYING A WOOD DISTRIBUTION ENHANCING AGENT COMPRISING AMINE OXIDE(S) | LONZA INC. | 2002-11-26 | — | — | US | disclosed |
| US-20020061366-A1 | Methods for enhancing penetration of wood preservatives | LONZA INC. | 2002-05-23 | — | — | US | disclosed |
| EP-1165297-A2 | METHODS FOR ENHANCING PENETRATION OF WOOD PRESERVATIVES | LONZA INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1140797-A1 | PRODUCTION OF ACRYLIC MONOMERS | Ciba Specialty Chemicals Water Treatments Limited (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000059696-A2 | METHODS FOR ENHANCING PENETRATION OF WOOD PRESERVATIVES | LONZA INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| WO-2000041996-A1 | PRODUCTION OF ACRYLIC MONOMERS | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2000-07-20 | — | — | WO | disclosed |
| US-4197373-A | N,N'-BIS(1-HYDROXY-2,2,2-TRICHLOROETHYL)MELAMINE AND ITS DERIVATIVES | PENNWALT CORPORATION (US) | 1980-04-08 | — | — | US | disclosed |
| US-4152497-A | Compounds containing the 2,2,2-trichloroethyl group as flame retardants for polyurethanes | PENNWALT CORPORATION (US) | 1979-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061366-A1 | Methods for enhancing penetration of wood preservatives | PNN, CD69, AKR1C2 | KDM4E 519/4885HMGCR 3220/4885CHRM1 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.