⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8373854 | 0.97 | LMNA (0.35) | — | |
| Hydrochloric Acid SCHEMBL3026920 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL8373770 | 0.97 | KDM4E (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL15541598 | 0.84 | NOS1 (0.39) | — | |
| SCHEMBL31441327 | 0.83 | — | — | |
| SCHEMBL16280996 | 0.80 | KDM4E (0.42) | — | |
| SCHEMBL156638 | 0.78 | — | — | |
| SCHEMBL95243 | 0.78 | — | — | |
| SCHEMBL1133260 | 0.78 | — | — | |
| SCHEMBL8709491 | 0.78 | HMGCR (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1509 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291185-A1 | CONJOINT THERAPY FOR TREATING SEIZURE DISORDERS | Xenon Pharmaceuticals Inc. (CA) | 2023-12-20 | — | — | EP | claimed |
| US-20230192646-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES | UCB Biopharma SRL (BE) | 2023-06-22 | — | — | US | claimed |
| EP-4081299-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES | UCB Biopharma SRL (BE) | 2022-11-02 | — | — | EP | claimed |
| CN-114867525-A | Dihydrocyclopentaisoquinoline derivatives | UCB生物制药有限责任公司 | 2022-08-05 | — | — | CN | claimed |
| EP-4031548-A1 | METHODS OF USE FOR KV7 CHANNEL ACTIVATORS | Knopp Biosciences LLC (US) | 2022-07-27 | — | — | EP | claimed |
| CN-114478389-A | Isotopic psychoactive substance labeled compound, preparation method, application and application thereof | 公安部第三研究所 | 2022-05-13 | — | — | CN | claimed |
| CN-114206892-A | (2-acetamido) thio-beta-D-galactopyranoside derivatives | 爱杜西亚药品有限公司 | 2022-03-18 | — | — | CN | claimed |
| WO-2021130255-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES | UCB Biopharma SRL (BE) | 2021-07-01 | — | — | WO | claimed |
| CN-112839654-A | Process for preparing substituted pyridone-containing tricyclic compounds | 爱彼特生物制药公司 | 2021-05-25 | — | — | CN | claimed |
| WO-2021055538-A1 | METHODS OF USE FOR KV7 CHANNEL ACTIVATORS | KNOPP BIOSCIENCES LLC (US) | 2021-03-25 | — | — | WO | claimed |
| CN-1131146-A | Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide | SUMITOMO CHEMICAL CO (JP) | 1996-09-18 | — | — | CN | claimed |
| EP-0715618-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | claimed |
| WO-1995033464-A2 | RETROVIRAL PROTEASE INHIBITOR COMBINATIONS | G.D. SEARLE & CO. (US) | 1995-12-14 | — | — | WO | claimed |
| EP-0430738-A2 | Use of an imidazopyridine for the manufacture of anesthetic medicaments | SYNTHELABO (FR) | 1991-06-05 | — | — | EP | claimed |
| EP-0143001-B1 | PYRIMIDOISOQUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-10 | — | — | EP | claimed |
| EP-0312157-A2 | Tetrapeptide renin inhibitors having a novel c-terminal amino acid | MERCK & CO. INC. (US) | 1989-04-19 | — | — | EP | claimed |
| EP-0312158-A2 | Tetrapeptide renin inhibitors having novel c-terminal amino acid amide | MERCK & CO. INC. (US) | 1989-04-19 | — | — | EP | claimed |
| EP-0303863-A2 | Benzenesulfonyl carboxamide compounds, intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1989-02-22 | — | — | EP | claimed |
| US-4673676-A | Pyrimidoisoquinoline derivatives useful for treating allergies | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-16 | — | — | US | claimed |
| EP-0143001-A2 | Pyrimidoisoquinoline derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-05-29 | — | — | EP | claimed |