SCHEMBL4669249

SCHEMBL4669249

Cc1ccc(C(c2ccccc2)c2ccc(C)cc2N=C=O)c(N=C=O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.41
TRPA1 O75762 1/20 0.37
BRD4 O60885 1/20 0.35
FTO Q9C0B1 1/20 0.34
TP53 P04637 3/20 0.33
MAPT P10636 3/20 0.33
HTT P42858 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ACP3 P15309 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ELANE P08246 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CACNA1G O43497 1/20 0.32
CACNA2D1 P54289 1/20 0.32
CACNA1B Q00975 1/20 0.32
CACNB1 Q02641 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7588864 0.81 CYP3A4 (0.44) CYP3A4TRPA1MAPTHTTMEN1
SCHEMBL635874 0.81 CYP3A4 (0.43) CYP3A4TRPA1BRD4MAPTMEN1
SCHEMBL300705 0.80 CYP3A4 (0.44) CYP3A4TRPA1KMT2AALDH1A1HPGD
SCHEMBL9558693 0.78 CYP3A4 (0.44) CYP3A4TRPA1MAPTHTTMEN1
SCHEMBL4139131 0.77 CYP3A4 (0.46) CYP3A4TRPA1KMT2AALDH1A1TDP1
SCHEMBL23721637 0.76 CYP3A4 (0.45) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL698040 0.72 CYP3A4 (0.44) CYP3A4TRPA1FTOTP53MAPT
SCHEMBL6229251 0.72 CACNA2D1 (0.43) CYP3A4BRD4TP53MAPTHTT
SCHEMBL10702033 0.72 CYP3A4 (0.38) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL30519851 0.72 CYP3A4 (0.50) CYP3A4TRPA1FTOMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000298-A1 TRANSPARENT BARRIER SHEET AND METHOD FOR PRODUCING TRANSPARENT BARRIER SHEET Konica Minolta Medical & Graphic, Inc. (JP) 2008-12-10 EP disclosed
US-20070224428-A1 Transparent barrier sheet and production method of transparent barrier sheet KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-09-27 US disclosed