Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL466944 | 1.00 | CA12 (0.53) | CA12CA14CA2MMP2MMP9 | |
| SCHEMBL29367675 | 0.98 | CA12 (0.54) | CA12CA14CA2MMP2MMP9 | |
| SCHEMBL409050 | 0.98 | CA12 (0.54) | CA12CA14CA2MMP2MMP9 | |
| SCHEMBL29478385 | 0.98 | CA12 (0.54) | CA12CA14CA2MMP2MMP9 | |
| SCHEMBL298855 | 0.98 | CA12 (0.54) | CA12CA14CA2MMP2MMP9 | |
| SCHEMBL42286 | 0.98 | CA12 (0.54) | CA12CA14CA2MMP2MMP9 | |
| SCHEMBL42287 | 0.98 | CA12 (0.54) | CA12CA14CA2MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL21433625 | 0.97 | CA12 (0.53) | CA12CA14CA2MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL21433626 | 0.97 | CA12 (0.53) | CA12CA14CA2MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL6420699 | 0.97 | CA12 (0.53) | CA12CA14CA2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585486-B1 | NEW OCTAPEPTIDIC COMPOUNDS AND THEIR USE IN THERAPY | IPSEN PHARMA SAS (FR) | 2014-05-14 | — | — | EP | claimed |
| EP-2585486-A1 | NOVEL OCTAPEPTIDE COMPOUNDS AND THERAPEUTIC USE THEREOF | Ipsen Pharma S.a.S. (FR) | 2013-05-01 | — | — | EP | claimed |
| WO-2011161332-A1 | NOVEL OCTAPEPTIDE COMPOUNDS AND THERAPEUTIC USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2011-12-29 | — | — | WO | claimed |
| EP-2399931-A1 | New octapeptide compounds and their therapeutic use | IPSEN PHARMA S.A.S. (FR) | 2011-12-28 | — | — | EP | claimed |
| CN-108137676-A | gp120 neutralizing antibodies and uses thereof | 美国政府(由卫生和人类服务部的部长所代表) | 2018-06-08 | — | — | CN | disclosed |
| EP-2585486-B1 | NEW OCTAPEPTIDIC COMPOUNDS AND THEIR USE IN THERAPY | IPSEN PHARMA SAS (FR) | 2014-05-14 | — | — | EP | disclosed |
| EP-2585486-A1 | NOVEL OCTAPEPTIDE COMPOUNDS AND THERAPEUTIC USE THEREOF | Ipsen Pharma S.a.S. (FR) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011161332-A1 | NOVEL OCTAPEPTIDE COMPOUNDS AND THERAPEUTIC USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2011-12-29 | — | — | WO | disclosed |
| EP-2399931-A1 | New octapeptide compounds and their therapeutic use | IPSEN PHARMA S.A.S. (FR) | 2011-12-28 | — | — | EP | disclosed |