SCHEMBL298855

SCHEMBL298855

C[C@@H](Nc1cccc2ccccc12)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.54
CA14 Q9ULX7 2/20 0.54
CA2 P00918 1/20 0.54
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP14 P50281 1/20 0.54
KDM4E B2RXH2 5/20 0.51
CYP3A4 P08684 3/20 0.51
CYP1A2 P05177 2/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
GAA P10253 1/20 0.51
NPC1 O15118 1/20 0.51
CYP2D6 P10635 1/20 0.51
RAB9A P51151 1/20 0.51
MEN1 O00255 5/20 0.51
KMT2A Q03164 5/20 0.51
MAPT P10636 4/20 0.51
TNNI3 P19429 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL409050 1.00 CA12 (0.54) CA12CA14CA2MMP2MMP9
SCHEMBL29367675 1.00 CA12 (0.54) CA12CA14CA2MMP2MMP9
SCHEMBL42287 1.00 CA12 (0.54) CA12CA14CA2MMP2MMP9
SCHEMBL29478385 1.00 CA12 (0.54) CA12CA14CA2MMP2MMP9
SCHEMBL42286 1.00 CA12 (0.54) CA12CA14CA2MMP2MMP9
Hydrochloric Acid SCHEMBL21433626 0.98 CA12 (0.53) CA12CA14CA2MMP2MMP9
Ammonia Solution, Strong SCHEMBL466944 0.98 CA12 (0.53) CA12CA14CA2MMP2MMP9
Hydrochloric Acid SCHEMBL21433625 0.98 CA12 (0.53) CA12CA14CA2MMP2MMP9
Ammonia Solution, Strong SCHEMBL466943 0.98 CA12 (0.53) CA12CA14CA2MMP2MMP9
Hydrochloric Acid SCHEMBL6420699 0.98 CA12 (0.53) CA12CA14CA2MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 766 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12459973-B2 Peptide compounds for reducing side effects of CB1 receptor agonists UNIVERSITAT DE BARCELONA (ES) 2025-11-04 US claimed
EP-4358989-A2 BICYCLIC PEPTIDYL PAN-RAS INHIBITORS Ohio State Innovation Foundation (US) 2024-05-01 EP claimed
EP-4041748-B1 PEPTIDE COMPOUNDS FOR REDUCING SIDE EFFECTS OF CB1 RECEPTOR AGONISTS UNIV BARCELONA (ES) 2024-05-01 EP claimed
CN-116554266-B Nanometer antibacterial peptide for targeted killing of gram-positive bacteria, preparation method and application 东北农业大学 2024-04-09 CN claimed
EP-4337676-A1 ANTIGEN-BINDING AND ANTIGEN DEGRADATION CONSTRUCTS Entrada Therapeutics, Inc. (US) 2024-03-20 EP claimed
US-20240059737-A1 PEPTIDE COMPOUNDS FOR REDUCING SIDE EFFECTS OF CB1 RECEPTOR AGONISTS UNIVERSITAT POMPEU FABRA (ES) 2024-02-22 US claimed
CN-116162130-B Enzymolysis-resistant nano antibacterial peptide and preparation method and application thereof 东北农业大学 2023-10-17 CN claimed
CN-116730969-A Beta-lapachone-amino acid conjugate, and preparation method and application thereof 中国药科大学 2023-09-12 CN claimed
CN-116554266-A Nanometer antibacterial peptide for targeted killing of gram-positive bacteria, preparation method and application 东北农业大学 2023-08-08 CN claimed
CN-116162130-A Enzymolysis-resistant nano antibacterial peptide and preparation method and application thereof 东北农业大学 2023-05-26 CN claimed
EP-0417165-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY. EASTMAN KODAK CO (US) 1991-03-20 EP claimed
EP-0400051-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY. EASTMAN KODAK CO (US) 1990-12-05 EP claimed
EP-0156280-B1 PROCESS FOR THE PREPARATION OF PEPTIDE INTERMEDIATES POOR IN RACEMATES, BELONGING TO GONADORELIN AND GONADORELIN ANALOGUES, THEIR SYNTHESIS AND INTERMEDIATES OBTAINED BY THIS PROCESS HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-07 EP claimed
WO-1989010933-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY EASTMAN KODAK COMPANY (US) 1989-11-16 WO claimed
WO-1989007110-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY EASTMAN KODAK COMPANY (US) 1989-08-10 WO claimed
US-4691008-A COUPLING A URETHANE-BLOCKED TRIPEPTIDE AND A PEPTIDE WITH A FREE AMINE USING A CONDENSATION AGENT HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-01 US claimed
US-4673665-A INDUCE OVULATION BY USING A GESTAGEN FOLLOWED BY LUTEINIZING HORMONE HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-16 US claimed
EP-0192742-A1 CYCLIC POLYPEPTIDES HAVING MU-RECEPTOR SPECIFICITY GIBSON-STEPHENS NEUROPHARMACEUTICALS, INC. (US) 1986-09-03 EP claimed
WO-1986001516-A1 CYCLIC POLYPEPTIDES HAVING MU-RECEPTOR SPECIFICITY GIBSON-STEPHENS NEUROPHARMACEUTICALS, INC. (US) 1986-03-13 WO claimed
EP-0156280-A2 Process for the preparation of peptide intermediates poor in racemates, belonging to gonadorelin and gonadorelin analogues, their synthesis and intermediates obtained by this process HOECHST AKTIENGESELLSCHAFT (DE) 1985-10-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12459973-B2 Peptide compounds for reducing side effects of CB1 receptor agonists CNR2, CNR1, OPRD1 CA12 2557/4885CA14 1942/4885CA2 1256/4885
US-20240059737-A1 PEPTIDE COMPOUNDS FOR REDUCING SIDE EFFECTS OF CB1 RECEPTOR AGONISTS CNR2, CNR1, OPRD1 CA12 2650/4885CA14 1982/4885CA2 1367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.