Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669466 | 1.00 | MEN1 (0.39) | MEN1KMT2ARAF1PKMYT1HDAC1 | |
| SCHEMBL13980255 | 0.92 | MEN1 (0.39) | MEN1KMT2ARAF1PKMYT1HDAC1 | |
| SCHEMBL4667868 | 0.91 | RAF1 (0.43) | MEN1KMT2ARAF1HDAC1HDAC6 | |
| SCHEMBL4670669 | 0.91 | MEN1 (0.42) | MEN1KMT2AHDAC1HDAC6L3MBTL1 | |
| SCHEMBL4668484 | 0.87 | MEN1 (0.44) | MEN1KMT2AHDAC1HDAC6MAPT | |
| SCHEMBL4668517 | 0.86 | MEN1 (0.43) | MEN1KMT2AHDAC1HDAC6L3MBTL1 | |
| SCHEMBL4755393 | 0.86 | MEN1 (0.43) | MEN1KMT2AHDAC1HDAC6L3MBTL1 | |
| SCHEMBL4754383 | 0.85 | MEN1 (0.41) | MEN1KMT2AHDAC1L3MBTL1GSK3B | |
| SCHEMBL4669255 | 0.85 | MEN1 (0.41) | MEN1KMT2AHDAC1L3MBTL1GSK3B | |
| SCHEMBL4668510 | 0.84 | NAMPT (0.47) | MEN1KMT2AHDAC1HDAC6NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | claimed |
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |