Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 15/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754745 | 1.00 | NAMPT (0.47) | NAMPTHDAC3NCOR2HDAC1HDAC2 | |
| SCHEMBL4755393 | 0.90 | MEN1 (0.43) | NAMPTHDAC3NCOR2HDAC1HDAC2 | |
| SCHEMBL4668517 | 0.90 | MEN1 (0.43) | NAMPTHDAC3NCOR2HDAC1HDAC2 | |
| SCHEMBL4787691 | 0.89 | MEN1 (0.43) | HDAC3NCOR2HDAC1HDAC2HDAC4 | |
| SCHEMBL4787699 | 0.89 | MEN1 (0.43) | HDAC3NCOR2HDAC1HDAC2HDAC4 | |
| SCHEMBL4787706 | 0.89 | MEN1 (0.43) | HDAC3NCOR2HDAC1HDAC2HDAC4 | |
| SCHEMBL4017825 | 0.88 | MMP1 (0.50) | HDAC4MEN1KMT2A | |
| SCHEMBL4754759 | 0.85 | MEN1 (0.42) | HDAC3NCOR2HDAC1HDAC2HDAC4 | |
| SCHEMBL4018968 | 0.85 | MEN1 (0.44) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL4669474 | 0.85 | MEN1 (0.42) | HDAC3NCOR2HDAC1HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | claimed |
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | claimed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |