Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754641 | 0.93 | MEN1 (0.42) | HPGDALDH1A1MEN1KMT2AHDAC4 | |
| SCHEMBL4667869 | 0.93 | MEN1 (0.42) | HPGDALDH1A1MEN1KMT2AHDAC4 | |
| SCHEMBL4018968 | 0.90 | MEN1 (0.44) | HPGDALDH1A1MEN1KMT2AHDAC4 | |
| SCHEMBL4017825 | 0.90 | MMP1 (0.50) | HPGDALDH1A1MEN1KMT2AHDAC4 | |
| SCHEMBL4017742 | 0.89 | MMP1 (0.53) | HPGDALDH1A1MEN1KMT2AHDAC4 | |
| SCHEMBL4015839 | 0.87 | MEN1 (0.44) | HPGDALDH1A1MEN1KMT2AHDAC4 | |
| SCHEMBL4017504 | 0.86 | HPGD (0.53) | HPGDALDH1A1MEN1KMT2AHDAC4 | |
| SCHEMBL4668491 | 0.86 | KDM4E (0.48) | HPGDALDH1A1MEN1KMT2AHDAC4 | |
| SCHEMBL4752607 | 0.86 | KDM4E (0.48) | HPGDALDH1A1MEN1KMT2AHDAC4 | |
| SCHEMBL13982459 | 0.86 | HPGD (0.45) | HPGDALDH1A1MEN1KMT2AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |