Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697937 | 0.86 | MEN1 (0.55) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL403150 | 0.78 | ALDH1A1 (0.63) | MEN1KMT2AHPGDALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL3228101 | 0.76 | ALDH1A1 (0.62) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL3788527 | 0.76 | MEN1 (0.60) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL6016478 | 0.76 | MEN1 (0.69) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL29774207 | 0.76 | MEN1 (0.60) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL5264050 | 0.74 | ALDH1A1 (0.65) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL4279782 | 0.74 | MEN1 (0.59) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL8085536 | 0.74 | MEN1 (0.63) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL8294634 | 0.74 | ALDH1A1 (0.69) | MEN1KMT2AHPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937652-A1 | PYRIMIDINE AMIDE COMPOUNDS AS PGDS INHIBITORS | Aventis Pharmaceuticals Inc. (US) | 2008-07-02 | — | — | EP | claimed |
| WO-2007041634-A1 | PYRIMIDINE AMIDE COMPOUNDS AS PGDS INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2007-04-12 | — | — | WO | claimed |