Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213004 | 0.89 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8383976 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8388406 | 0.77 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL215587 | 0.76 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8385000 | 0.76 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL8388459 | 0.76 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL8386114 | 0.76 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL8384018 | 0.75 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL8389357 | 0.75 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL8385278 | 0.74 | PTGS2 (0.76) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479385-B1 | Use of cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia | SEARLE LLC (US) | 2008-07-02 | — | — | EP | claimed |