SCHEMBL4669969

SCHEMBL4669969

CCCC(C)(O[C]=O)c1ccc(C)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
GAA P10253 1/20 0.33
ESR1 P03372 6/20 0.33
ESR2 Q92731 4/20 0.33
AR P10275 1/20 0.33
CNR2 P34972 2/20 0.31
CNR1 P21554 1/20 0.31
KIF11 P52732 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA5A P35218 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4670012 0.86 TSHR (0.40) TSHRNPC1MAPTRAB9ACA1
SCHEMBL4669945 0.84 MAPK1 (0.36) TSHRMAPTRAB9AGAA
SCHEMBL4670344 0.81 TSHR (0.34) TSHRNPC1MAPTRAB9AGAA
SCHEMBL4673647 0.78 GAA (0.33) TSHRNPC1MAPTRAB9AGAA
SCHEMBL4669973 0.76 TSHR (0.38) TSHRNPC1MAPTRAB9AGAA
SCHEMBL138150 0.74 TSHR (0.46) TSHRNPC1MAPTRAB9AGAA
SCHEMBL4669940 0.73 TSHR (0.37) TSHRNPC1MAPTRAB9ACA1
SCHEMBL4675618 0.69 MAPK1 (0.39) TSHRMAPT
SCHEMBL12981405 0.69 TSHR (0.50) TSHRNPC1MAPTRAB9AESR1
SCHEMBL5048108 0.68 TSHR (0.39) TSHRNPC1MAPTRAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811475-A REACTING A CARBON WITH A POLYMER HAVING A REACTIVE GROUP AND A HYDROLYZABLE TERT-ALKYL ACRYLIC ESTER; PRINTING INKS; DIELECTRICS; HIGH ELECTRICAL RESISTANCE NIPPON OIL CO., LTD. (JP) 1998-09-22 US claimed
US-20080124552-A1 Particle With Rough Surface For Plating Or Vapor Deposition NISSHINBO INDUSTRIES, INC. (JP) 2008-05-29 US disclosed
US-5821277-A Thermosetting and procuring compositions for color filters and method for making the same NIPPON OIL CO., LTD. (JP) 1998-10-13 US disclosed
US-5811475-A REACTING A CARBON WITH A POLYMER HAVING A REACTIVE GROUP AND A HYDROLYZABLE TERT-ALKYL ACRYLIC ESTER; PRINTING INKS; DIELECTRICS; HIGH ELECTRICAL RESISTANCE NIPPON OIL CO., LTD. (JP) 1998-09-22 US disclosed
EP-0753548-A2 Method for producing carbonaceous material NIPPON OIL COMPANY, LIMITED (JP) 1997-01-15 EP disclosed