SCHEMBL138150

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL135667	0.80	MAPK1 (0.56)	TSHRMAPTMAPK1ALDH1A1CYP3A4
	SCHEMBL9461	0.78	MAPK1 (0.43)	NPC1MAPTMAPK1ALDH1A1GAA
	SCHEMBL1456484	0.77	CYP19A1 (0.41)	RAB9AMAPK1ALDH1A1ALOX15KIF11
	SCHEMBL5048108	0.77	TSHR (0.39)	TSHRNPC1MAPTRAB9ACA1
	SCHEMBL6776985	0.76	TSHR (0.40)	TSHRACHEMAPK1ALDH1A1CYP3A4
	SCHEMBL4670012	0.76	TSHR (0.40)	TSHRNPC1MAPTRAB9ACA1
	SCHEMBL11152162	0.74	MAPK1 (0.59)	TSHRNPC1MAPTRAB9ACA1
	SCHEMBL21845090	0.74	TSHR (0.57)	TSHRNPC1MAPTRAB9ACA1
	SCHEMBL4669940	0.74	TSHR (0.37)	TSHRNPC1MAPTRAB9ACA1
	SCHEMBL4669969	0.74	TSHR (0.38)	TSHRNPC1MAPTRAB9ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 729 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.