Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670468 | 0.88 | PARP15 (0.42) | PARP15PARP10NPC1MTORPARP2 | |
| SCHEMBL4670081 | 0.86 | ADRB2 (0.42) | PARP15PARP10NPC1MTORPARP2 | |
| SCHEMBL4677832 | 0.86 | PARP15 (0.43) | PARP15PARP10NPC1MTORPARP2 | |
| Water SCHEMBL4673066 | 0.85 | ADRB2 (0.41) | PARP15PARP10MTORPARP2OPRM1 | |
| SCHEMBL4670057 | 0.85 | PARP15 (0.42) | PARP15PARP10NPC1MTORPARP2 | |
| SCHEMBL4670624 | 0.85 | PARP15 (0.40) | PARP15PARP10MTORPARP2OPRM1 | |
| Water SCHEMBL4672106 | 0.85 | ADRB2 (0.41) | PARP15PARP10MTORPARP2OPRM1 | |
| SCHEMBL4670421 | 0.85 | PARP10 (0.42) | PARP15PARP10PARP2OPRM1OPRL1 | |
| SCHEMBL4670091 | 0.84 | PARP15 (0.41) | PARP15PARP10NPC1MTORPARP2 | |
| SCHEMBL6301319 | 0.84 | PARP10 (0.41) | PARP15PARP10PARP2OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054881-B1 | NOVEL SULFONAMIDE SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER CORP (US) | 2008-07-30 | — | — | EP | disclosed |